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The full press release referenced in this article can be found here .

While this sensation is harmless and does not mean the medication isnt working, it can contribute to needle anxiety. Bolded Lead Sentence: Removing the chill from the medication allows the liquid to enter the subcutaneous tissue (the fat layer just under the skin) more gently

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Working with a PlexusDx provider helps distinguish between normal sulfur burps (which resolve with dietary modification) and burps paired with severe bloating, vomiting, or abdominal pain (which warrant immediate evaluation for gastric obstruction)