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Immunohistochemical methods were used to study the relationship between iron deposition, iron processing protein expression, and renal tubular injury in renal biopsies of CKD patients and healthy controls

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In line with the intracellular contributions to these clinical findings, correlation of intraepithelial cell GSH levels to FEV 1 was considerably stronger than the relationship in BAL fluid, supporting the overall importance of endogenous epithelial cell responses to clinical outcomes

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