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It gained popularity due to research exploring its potential role in longevity and healthy aging

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Large-scale randomised controlled trials, including the STEP 1 trial (Wilding et al., NEJM 2021) for semaglutide 2.4 mg, have demonstrated clinically meaningful and sustained weight loss in adults with obesity or overweight with weight-related comorbidities

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Code and associated phenotypic data to replicate the analyses presented in this work can be obtained by contacting the corresponding authors (please also see the Data availability statement)

First, peptides have proven clinical utility across multiple therapeutic areas, with particular success in endocrine, oncological, and rare disease applications