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However, you may be able to avoid invasive surgery with newer injection-based and image-guided procedures

Patient safety advice: Attend all scheduled monitoring appointments without fail Report any new urinary symptoms, bone pain, or unexplained weight loss immediately Understand that TRT may need to be stopped if PSA rises or other concerns emerge Maintain healthy lifestyle factors (exercise, weight management, smoking cessation) Continue regular cancer surveillance as recommended by the oncology team For gel formulations, wash hands after application and cover application sites with clothing to prevent transfer to others Report suspected side effects via the MHRA Yellow Card scheme The decision to continue TRT should be reviewed regularly, typically annually, reassessing the risk-benefit balance in light of monitoring results and any new evidence

Any successful weight management program requires professional guidance to achieve the best health outcomes and long-term results

doi: 10.1093/infdis/jiaa620 146 OuGXuHWuJWangSChenYDengLet al

Reason for escalation: gradual titration helps reduce GI-related effects and aligns with clinical study structures