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Sources The Effectiveness of Cobalamin (B12) Treatment for Autism Spectrum Disorder: A Systematic Review and Meta-Analysis Journal of Personalized Medicine (2021) Vit B12 supplement of 500 g/d for eight weeks does not normalize urinary methyl-malonic acid or other biomarkers of vitamin B12 status in elderly people J Nutr

Third, a variety of confounding factors could not be considered in multivariate analyses due to the small sample size

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This is a strong study design though with only 6 participants, the statistical power is very limited

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(ii) studies on patients who have suffered liver failure following APAP overdose