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They are not interchangeable dose-for-dose

Need to work out reconstitution concentrations or convert a dose into insulin-syringe units

In contrast, the long-term use of artificial cyanocobalamin supplements does not have a direct biological effect and must first be converted in the body into one of the three natural forms of B12

Because of this, the same vial can usually be used for multiple doses when stored and handled correctly

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For a longer time of time, the powder remains strong, stable, and usable when stored properly