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Non-GST protein sequences, short protein sequences (less than 100 amino acids) and fragmented split sequences were excluded from future analysis

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The safety, tolerability, pharmacokinetics and pharmacodynamics of an optimized dual GLP-1/GIP receptor agonist (BGM0504) in healthy volunteers: a dose-escalation phase I study

In adults, IGF-1 and its analogues have been shown to reduce neuronal death and protect neurons against insults like stroke, Alzheimers disease, Parkinsons disease, and more

Furthermore, the simultaneous administration of 25% ethanol (at a single dose of 2.9 g/kg) and a 12.5% body area burn in mice resulted in a decrease in the expression of TJs and mucins, specifically affecting the genes claudin-4, claudin-8 in both ileal and colonic epithelial cells, as well as claudin-2 and mucin-3 in the intestinal tract [279]