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Recent studies of AMG 509, a STEAP1-directed T cell engager molecule under development for the treatment of prostate cancer, have also shown that targeting STEAP1 homodimers and STEAP1/2 heterotrimers leads to T cell-dependent cellular cytotoxicity 115

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In addition, I will continue to work diligently with patients on dietary modification and advancement of their aerobic and resistance exercises to improve weight parameters

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The dose may need adjusting, or other changes may be needed to stay safe while continuing treatment