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Remarkably, we found that the knockdown of dLS GLP-1Rs did not influence food intake or body weight in mice at the baseline, regardless of dietary conditions (Supplemental Figure 3, AE)

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3 Medicaid coverage for weight-loss drugs Medicaid is required to provide coverage for any FDA-approved drug that meets the federal definition of a covered outpatient drug and for which the manufacturer has entered into a rebate agreement with the Department of Health and Human Services Secretary (i.e., the Medicaid Drug Rebate Program [MDRP])

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Although leave-one-out and Baujat analyses were performed, they did not meaningfully reduce heterogeneity, indicating that the variability is intrinsic to the studies themselves