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Therefore, overuse and rapid depletion of glutathione results in a deficiency of methylcobalamin and a number of neuropathological disease states related to a downstream neurotransmitter imbalance (James et al., 2004

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Both plasma basic carboxypeptidases, carboxypeptidase B2 and carboxypeptidase N, regulate vascular leakage activity in mice

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Emerging evidence suggests these elevated enzymatic levels are sustained through combinatorial mechanisms: enhanced biosynthesis, increased transporter activity, and reduced catabolism