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However, the data indicates that this peptide might not significantly affect the frequency of growth hormone pulses or the peak levels reached during each pulse

[PubMed] [Google Scholar] Ballatori N, Jacob R, Barrett C, Boyer JL

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Its defining characteristic in the research literature is a "clean" hormonal profile: robust, dose-dependent GH release without the meaningful elevations in cortisol, prolactin, ACTH, or appetite seen with earlier-generation secretagogues

J Clin Invest 2007

combining them with treatment may reduce the dose needed Always tell your provider about every supplement, medication, and therapy you are using so they can design a protocol that accounts for the full picture