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Still, these findings point to the potential neuroprotective and cerebrovascular benefits of GLP-1 drugs, according to the researchers, who added that future randomized trials in these patient populations are needed to validate our findings and establish causality. Novo is already working toward that end

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An extensive systematic review and meta-analysis published in the Journal of the American Medical Association (JAMA) Ophthalmology found that while treatment with semaglutide did not increase or decrease risk for diabetic retinopathy (DR), it was associated with increased occurrence of nonarteritic anterior ischemic optic neuropathy (NAION)