Alternative processing of proglucagon leads to the formation of glucagon, GRPP and major pro-glucagon fragment (MPGF) in the pancreas, whereas in the gut and brain glicentin, GRPP, oxyntomodulin, GLP-1 and GLP-2 are formed ( Figure 1 )
Hypokalemia: All insulin containing products can cause hypokalemia, which may be life-threatening
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References WeGovy Label: accessdata.fda.gov/ JAMA Network Open Study: jamanetwork.com National Library of Medicine: pmc.ncbi.nlm.nih.gov Journal of Clinical Endocrinology & Metabolism : academic.oup.com University of Colorado Anschutz Medical Campus Study: medschool.cuanschutz.edu Health.com Study: health.com FDA Documentation: fda.gov JBMR Plus: academic.oup.com/jbmrplus Harvard University: health.harvard.edu
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Given these anti-inflammatory effects, there is speculation that GLP-1 medicines could impair host immune defenses
