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The in vitro metabolic data established the half-life of AOD9604 in human serum and identified the primary metabolic pathways responsible for its clearance
Its effects are systemic despite being locally administered, with preliminary trial evidence showing accelerated repair in distant injuries including tendon tears, ulcers, and damaged blood vessels
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While that is an opinion, it reflects a growing sentiment that doctors stepping outside the bounds of evidence-based medicine with peptides are leaving themselves exposed to lawsuits
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This mechanism supports cellular resilience by upregulating endogenous antioxidants, including heme oxygenase-1 (HO-1), thus reducing oxidative stress, preventing mitochondrial dysfunction, and limiting apoptosis [11, 20, 23, 41, 42]
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