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In the context of extremely low levels of SAMe, Dnmt3a and Dnmt3b might demethylate 5mC via deamination to thymine, which confirmed the dynamic activity of DNMTs with methyltransferases and demethylases according to the levels of SAMe [67]

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DaboAJEzegbunamWWymanAEMoonJRailwahCLoraAet alTargeting c-Src reverses accelerated GPX-1 mRNA decay in chronic obstructive pulmonary disease airway epithelial cells