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This section focuses on the core issues in the translation process, providing a systematic reference for clinical implementation

What is PlexusDx's Microdose GLP-1 Protocol, and does it cause less stomach pain

doi: 10.12659/MSM.934116 191 HillRMRochaSParsonsJL

Considering the prolonged half-life of most GLP-1 agonists currently prescribed, it is unfeasible to withhold these agents for weeks prior to surgery to achieve normalisation of gastric function with unknown impact on aspiration rates, appreciating the detrimental effects of poorer glycaemic control on withholding these agents and associated higher risk of peri/postoperative complications (major cardiovascular events, poor wound healing, increased wound infection etc.)

Differential expression of microRNAs during melanoma progression: miR-200c, miR-205 and miR-211 are downregulated in melanoma and act as tumour suppressors

While inconsistent results on how well a drug works on a particular condition are not uncommon, this reinforces the need for more clinical trials to be done with humans rather than animals