In practice, though, many IBS-C patients on semaglutide need to be proactive with constipation-countering measures (more on strategies in the next section)
In February 2026, Novo Nordisk announced that the US Food and Drug Administration has approved Ozempic tablets, an oral form of semaglutide, with availability expected in the United States in the second quarter of 2026
Stephen Petrou, an emergency medicine physician and toxicology fellow with California Poison Control, said there were multiple factors contributing to the increase in overdoses.Not only is there rising social popularity of the drug, Petrou said, but theres also wider FDA indications for use.Semaglutide was patented by the Danish pharmaceutical company Novo Nordisk in 2012 and has been available in the United States since the FDA approved it in 2017
The product has demonstrated bioequivalence to the reference (innovator) drug, with its performance further validated through Phase III clinical studies conducted in direct comparison
Use as-needed rather than prophylactically
Regulators will demand real-world data proving these platforms sustain fat loss safely across populations