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It is important to acknowledge that the relationships we found between AC levels, MDD diagnosis, depression severity and depression profiles may be explained to some extent by shared distal environmental and lifestyle factors (e.g., comorbid somatic diseases, sedentary behavior, smoking, high-fat diet, alcohol consumption [61,62,63,64] that could act as confounder or mediators of the association

Research from Emory University and the National Institutes of Health has established glutathione status as a biomarker and therapeutic target in oxidative stress-related diseases

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Healthcare providers must monitor patients closely and educate them about risks

For example: Chronic mild stress inhibits mitochondrial function at respiratory chain complexes I, III, and IV.[ref] Lets dig into chronic stress further: Chronic stress: a cause of mitochondrial dysfunction