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GLP-1 drugs lower blood sugar only when it's high, unlike insulin, which works regardless of glucose levels

However, this peptide has been on the World Anti-Doping Agency (WADA) prohibited list under Class S0 (Non-Approved Substances) since 2022

ALC-CDDP-RT treatment increased the expressions of Quinone oxidoreductase1 (NQO1), SODIII, Heme Oxygenase (HO-1) and Glutathione-S Transferase (GST)

The team explained that these differences drive the variability in drug response among patients and lead to the weight-loss plateau

The case reports suggest that reductions of 15 to 25% from the original levothyroxine dose are common in patients experiencing significant weight loss on GLP-1 agonists

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