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Hepatitis C Virus core+1/ARF protein modulates the cyclin D1/pRb pathway and promotes carcinogenesis

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Mar 2019;23(5):2293-2301

GDF15 in appetite and exercise: essential player or coincidental bystander

Second, the development of new drugs requires additional and more detailed preclinical and clinical studies to determine whether long-term use is biotoxic, whether the drug has adverse effects on other peripheral organs or whether the drug candidate has a real therapeutic effect on the patients