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A commenter noted that a supplemental document posted August 11, 2025, created additional confusion by describing steps the proposed rule indicated were not performed and contradicting information in the rule itself

This allows time for: The medication to fully clear from your system Hormones and cycles to regulate Your body to adjust metabolically before IVF medications begin Because every patient is different, timing may vary, but a 2-3 month washout is a widely accepted baseline

A key part of this philosophy is protecting the body from damage linked to free radicals and oxidative stress

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Revijonijiet fijoloii, 2007, 87(4): 1409-1439