For example, a phase 2 RCT testing an inhibitor of 11-beta-hydroxysteroid dehydrogenase 1 (11-HSD1)an enzyme involved in the conversion of inert cortisone to active cortisol, which, when elevated in CSF, has been linked to cognitive declinefailed to find any cognitive benefit for AD patients with mild to moderate symptoms (Seckl, 2024)
However, all other cannabinoids, whether natural or synthetic, are prohibited in-competition
journal, Antioxidant effects of sulfur-containing amino acids
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They end up wasting more time with subtherapeutic doses than they saved by hoarding a compromised vial
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