Hofmann NA, Ortner A, Jacamo RO, Reinisch A, Schallmoser K, Fruewirth M, Diwoky C, Rohban R, Beham-Schmid C, Andreeff M , Strunk D
TP53 Mutant Acute Myeloid Leukemias comprise Stem-like Cell Enriched Cellular Hierarchy and are Vulnerable to Targeted Protein Degradation of c-MYC
The radioprotection studies of DHS were carried out in a mice model wherein intraperitoneal administration of DHS (2 mg/kg body weight for five consecutive days before irradiation and three times per week during the post-irradiation period) showed significant improvement in the 30-day survival against the lethal dose (8 Gy, -rays) of WBI (Table 2) [64]
Copper also participates in the synthesis of copper-dependent enzymes, including superoxide dismutase (SOD) (9), cytochrome c oxidase (10), tyrosinase (11), lysyl oxidase and dopamine (DA) -hydroxylase (12,13)
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