The K cat/ K m was 7 to 12 fold less than SeGST and TeGST, 4 to 5 fold less than GSTM1-1 and GSTP1-1 and 3 to 11 times more than GSTA1-1 and GSTM4-4 [23, 38]
- Combination of vitamin C, vitamin E, and milk thistle to suppress glutathione consumption
Additional Synergistic Nutrients Other compounds, such as alpha-lipoic acid, N-acetylcysteine, and zinc, are often included in antioxidant therapies to maximize efficacy
However, this is less likely if the body cannot synthesize glutathione from nutrients 21 , an ability that decreases with age
- From vitamin C to milk thistle
This creates more oxidative byproducts that glutathione helps neutralize