glp 1 levels in obesity GLP-1 Genetics: How Genes Affect Appetite, Semaglutide, and Tirzepatide Response Intestinal interleukin-22 enhances GLP-1 production

Current evidence suggests they are mostly neutral

11. Carney JA

Beyond peripheral blood, recent studies suggest that this systemic neutrophil priming may extend to tissue compartments, including the ovary, endometrium, and vascular endothelium, where activated neutrophils release proteases, ROS, and NETs that alter local microenvironments [20, 21]

If you weigh the knowns against the unknowns, especially around melanoma risk and manufacturing quality, the most defensible position is cautious skepticism: even if Melanotan 1 is theoretically safer than Melanotan 2, both sit on the wrong side of the riskbenefit equation for purely cosmetic tanning.

I didn't do anything

Abbasi, J