doi: 10.3389/fendo.2021.678055 [DOI] [PMC free article] [PubMed] [Google Scholar] 18
Importantly, GLP-1 receptors are found not only in neurons but also in glial cells, which mediate its effects on brain health by regulating energy balance and maintaining neural circuits
Prescriptions of liraglutide and semaglutide stratified by indication (with pre-existing DM or without pre-existing DM) and by year, are shown in Supplementary Table S2
Weight loss and improved glycemic control are therefore generally beneficial for reproductive health for example, weight reduction can raise testosterone levels and improve semen quality in obese menmdpi.compubmed.ncbi.nlm.nih.gov
It may be reasonable to focus on whether the combination of GLP-1RAs and SGLT2is, which are expected to have complementary effects based on large-scale clinical trial results, can further reduce cardiovascular and renal events in patients with diabetes
Endocrinology 154 , 48 (2013)