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Receptors for ghrelin are present in several systems and organs, including the brain, where they directly stimulate hunger and indirectly prevent low blood sugar by promoting the secretion of GH
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Alba M, Fintini D, Sagazio A, Lawrence B, Castaigne JP, Frohman LA, Salvatori R Once-daily administration of CJC-1295, a long-acting growth hormone-releasing hormone (GHRH) analog, normalizes growth in the GHRH knockout mouse