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(3) bispecific antibody, targeting TREM2 as a tetravalent TREM2 agonistic antibody that increases TREM2 activity by 100-fold, meanwhile targeting transferrin receptor, improved antibody brain entry by more than 10-fold
Nat Neurosci 16(2):13945 Tononi G, Cirelli C (2014) Sleep and the price of plasticity: from synaptic and cellular homeostasis to memory consolidation and integration
Patikorn et al., 2023)
Additionally, your doctor might explore transitioning you to more cost-effective oral medications, such as metformin or naltrexone/bupropion, to help you maintain your progress after tapering off completely
Ding K, Liu C, Li L, Yang M, Jiang N, Luo S, et al
Baillet, A
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