tirzepatide phase 3 study results Shows Superior Weight Loss Over Semaglutide in Trial Lilly orforglipron oral GLP-1 phase

Many patients on weekly injection schedules receive exactly four pens per month, aligning perfectly with the 28-day expiration window

ITT is estimating treatment as prescribed, but now we see a trend to estimating effect of treatment as it is taken by patients, which asks much more meaningful clinical questions for patients and prescribers. Outside of clinical trials, better understanding of real-world adherence also has economic implications

C., Pollard, E

Studies suggest that GLP-1s may cross the blood-brain barrier, which means they could affect the central nervous system

Proactive discussions about discontinuation are also appropriate when: You have achieved your treatment goals , such as reaching target HbA1c levels or desired weight loss, and wish to explore whether ongoing treatment is necessary

When combined with diet and exercise, patients who struggle with weight control can experience significant weight loss