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doi: 10.1111/j.1462-5822.2010.01474.x

GLP-1RA-induced reductions in protein intake, lower insulin/IGF-1 and negative energy balance converge to suppress mTOR signaling, reducing muscle protein synthesis [31]

Notably, neuroprotective effects are potentially conferred by both physiological and moderately elevated concentrations

Persistent abdominal pain, unexplained nausea, vomiting, or elevated pancreatic enzymes (amylase or lipase) warrant immediate medical evaluation and potential treatment discontinuation

The most clinically significant effect on electrolyte balance stems from gastrointestinal adverse effects

This treatment is most effective when accompanied by lifestyle changes