10.2174/1871527321666220111124047 CNS Neurol
Beyond their established role as energy substrates, SCFAs act as localized and systemic signaling molecules through G protein-coupled receptors (GPR41, GPR43, and GPR109A), thereby mediating bidirectional communication between the gastrointestinal tract and peripheral organs 165
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For spinal structures with naturally limited blood supply (particularly the intervertebral discs, which are largely avascular), this enhanced circulation to surrounding tissues can make a meaningful difference in healing capacity
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