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When managing patients taking opioid analgesics, particularly those who have been treated for an extended period of time, and/or with high doses for chronic pain, ensure that a multimodal approach to pain management, including mental health support (if needed), is in place prior to initiating an opioid analgesic taper

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Microdosing GLP-1s isnt FDA-approved, so insurers see it as experimental. And experimental treatments are almost always excluded from coverage