A randomized controlled trial in 167 older adults (50 years) found two-year supplementation with vitamin B 12 (10 g/day), along with folic acid (200 g/day), vitamin B6 (10 mg/day), riboflavin (5 mg/day), and vitamin D (10 g/day), had no effect on bone mineral density (total hip, femoral neck, or lumbar spine) compared to the control group only receiving vitamin D (10 g/day ) (116)
B-12 injections are a form of vitamin B-12 supplementation delivered through an intramuscular shot
Keeping that distinction in view prevents the most common error in this comparison: treating a standalone-monotherapy number for one and a combination number for the other as if they were measured the same way
In addition, 5%10% of the supplement dose was eliminated via urine as carnitine and acetylcarnitine, which resulted in a remaining bioavailability of less than 5% of the dose
J Lipid Res (2020) 61:3344
NAD through IV is proven to give you a faster, more effective outcome