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In normal physiological conditions, the brains antioxidant system efficiently reduces reactive oxygen species (ROS) produced during metabolic processes

Age-related changes in glutathione and lipid peroxide content in mouse synaptic mitochondria: Relationship to cytochrome c oxidase decline

Furthermore, melatonin has been used in several tissues to reduce the calcium uptake by the cells and modulate the expression of antioxidants [4,8,22,23,24,25,26,27]

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Franks F, Mathias S

Reduced norepinephrine turnover in interscapular brown adipose tissue of obese rats after ovariectomy