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Tirzepatide (Mounjaro, Zepbound) Tirzepatide is a dual GIP/GLP-1 agonist, meaning it acts on two receptors instead of one

As such, although morphologically and functionally similar, melanocytes and dendritic cells are not the same

It is generally limited to clinical trial or approved research channels

We appreciate the commenters for sharing their concern that ASM may encourage independent rural practices to consolidate or lead to practice closures

Some trials have favored administering high oral doses to achieve therapeutic effect

Therefore, we proposed conforming changes to 427.302(c) and to redesignate 427.302(c)(5) as 427.302(c)(6)