[DOI] [PMC free article] [PubMed] [Google Scholar] 21.Nielson C.M., Marshall L.M., Adams A.L., LeBlanc E.S., Cawthon P.M., Ensrud K., et al
By week four at the starting dose, many people feel theyve mostly adjusted and side effects are minimal
They feel like the medication isnt working because the scale hasnt moved much
Patients experiencing any sudden change in eyesight while taking semaglutide should urgently attend eye casualty or A&E
Diarrhea often peaks 2448 hours after injection and may resurface temporarily during dose increases
Patient-specific factors include age (older adults have more fragile blood vessels and thinner skin), genetic predisposition to easy bruising, nutritional status, and underlying medical conditions affecting coagulation or vascular integrity