The methods involve the reduction of Cu(II) in its complexes with neocuproine (NCN), bicinchoninic acid (BCA), and bathocuproine disulfonic acid (BCS) to the corresponding chromophoric Cu(I) complexes by the analyte
The consistency of the preclinical data across multiple studies and laboratories supports the mechanistic hypothesis
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Other flavonoids such as quercetin, kaempferol, myristin, apigenin, and luteolin also have antioxidative activity in many in vitro studies [45]
By determining their Lipinski value, the phytochemicals were also tested against the pharmaceuticals on the market using the SWISS-ADME server ( (Daina et al., 2017)
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