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It has been reported that iron deposition in LN leads to albuminuria (124) and that RTECs are responsible for reabsorbing most of the filtered iron

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In a recent study, pharmacological inhibition of NLRP3 inflammasome by MCC950 improved pathological damage and reduced inflammatory response in experimental pancreatitis ( 5 TCM used to relieve AP by targeting NLRP3 In Chinese medicine (CM), AP is classified under abdominal pain ( Futong ), spleen-heart pain ( Pi Xintong ), and pancreatic inflammation ( Yi Dan ) ( Gan Yu ), trauma, and invasion of exogenous pathogens ( Liu Yin ) (Wu, 2002), all of which may exacerbate the progression of AP

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Oxidative stress and diabetic neuropathy: pathophysiological mechanisms and treatment perspectives