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The primary practical consideration is selecting a suitable bacteriostatic agent

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For example, the dosage and the time needed to treat a person

A post hoc analysis suggested a GH cut-off of 5.1 g/L is more appropriate

Some research suggests they might affect prostaglandin synthesis, which could potentially influence smooth muscle contraction in the intestinal wall and alter gut transit time, though this effect is generally modest at recommended doses and the evidence is not conclusive