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Not always, but if symptoms dont settle in a couple of weeks (or if each stepup triggers prolonged issues) ask your prescriber about pausing or slowing titration

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The levels of serum LC, plasma malondialdehyde (MDA), and erythrocyte antioxidant enzymes activities [catalase (CAT), superoxide dismutase (SOD), glutathione peroxidase (GPx)] were measured before and after intervention