3 Urolithin A and sleep: current evidence For this mini-review, we utilized a hypothesis-based scoping review method where we conducted a search on PubMed, Scopus and Ovid utilizing the terms urolithin A and sleep, urolithin A and circadian, and urolithin A and serotonin or tryptophan. Our inclusion criteria were (1) original research articles, (2) published in English, (3) utilizing isolated urolithin A (no mixtures or parent polyphenols) and (4) including at least one outcome relevant to sleep or sleep-related biological mechanisms, with no constraints on publication date
[DOI] [PMC free article] [PubMed] [Google Scholar] 54.Deponte M
It was reported that BMAL1 deficient mice had altered circadian rhythm of circulating IGF-1 levels (Patel et al., 2016), and CRY1 and 2 deficient mice had reduced IGF-1 production (Ikeda et al., 2018)
Enhances immune system support by boosting white blood cell effectiveness
What I would suggest is that you start low at first, and then increase your dosage as your body gets accustomed to it
So you and I have gone down the rabbit hole on the FDA's attempt to try and regulate and rein in big industry, like big pharma and big medical
