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A number of researchers have reported that the activation of the SphK1/S1P signaling pathway marks the occurrence of autoimmune diseases, and the up-regulation of SphK1 is related to the pathogenesis of multiple sclerosis (Luo et al., 2017)

SA: Data curation, Investigation, Writing review & editing

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Evid Based Complement Alternat Med 2015:178128

In contrast, the prevalence of fatigue stands at around 5% in the general population and approximately 20% in non-cirrhotic community settings (9)

With careful monitoring and taking the right amount, diabetics can benefit from this crucial vitamin and lead healthy lives