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Circulating TMAO levels derived from dietary sources are positively correlated with CKD progression, while increased gut microbiota and TMAO derivatives are risk factors for cardiovascular events in patients with CKD (Castillo-Rodriguez et al., 2018

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Increased levels of -HB have been reported to improve symptoms of various age-related diseases [18], thereby providing a rationale for the development of therapeutic ketogenic interventions in neurodegenerative diseases [19]

Clinical effect sizes vary with indication, dosing, individual factors, and adherence

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The positive effects of GSH on seed germination and post-germination growth in the presence of Hg were also observed in other plant species, including tobacco, camelina, rice, alfalfa, and rape seed (Supplementary Figure S3)