No, topiramate is not a GLP-1 medication
The mechanism and timeline are the same as for male patients, with some adjustments in the protocol for patients in perimenopause or menopause where hormonal changes affect collagen synthesis and healing rates
However, other investigations did not show a correlation between penile sensitivity and PE 15, 16
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Any dysfunction in this chain of events caused by lack of cofactors or mitochondrial dysfunction would lead to reduced ATP formation and increased ROS, Ca 2+ and long chain fatty acid acyls and acylcarnitine buildup
Hypoperfusion is decreased blood flow to the brain, which means the brain doesnt receive sufficient oxygen and cant function normally