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Conclusion: This novel HDV infected model presents a valuable platform for the study of HDV infection mechanisms and antiviral drug responses

MS-DIAL: data-independent MS/MS deconvolution for comprehensive metabolome analysis

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Recent studies have explored small-molecule inducers, selenium-based compounds, and targeted nanodelivery approaches to restore GPX4 function or mimic its antioxidant capacity in ferroptosis-prone diseases, with therapeutic implications for OA and beyond ( In summary, GPX4 acts not only as a terminal antioxidant enzyme but also as a hub that integrates transcriptional, post-transcriptional, and nutritional cues