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However, rapid weight loss itselfespecially loss exceeding 1-2 pounds weeklycan temporarily shift thyroid hormone metabolism and TSH levels, a phenomenon called weight-loss-related thyroid adaptation

In addition, federal law prevents Medicare plans from covering weight loss drugs like Saxenda

Patch testing prior to use is advised

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Honest contraindication review: Active or recent malignancy, pregnancy, breastfeeding, uncontrolled diabetes, and severe pituitary disease are real contraindications

IGF-1 is typically composed of 70 amino acids but IGF-1 DES is a shortened analogue with only 67 amino acids