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Thus, we envisaged that the Pdx1-Cre;Trp53 R172H ;Rb f/f mouse model could be promising in preclinical investigations of the sensitivity and selectivity of exendin-4-based probes for the specific detection of insulinoma and compared the imaging outcomes with conventionally constructed mice insulinoma model

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Eur J Gastroenterol Hepatol 29(12):13851388

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This result in turn implies the occurnace of the thiol-ene click reaction between TPE-DCV and the intracellular thiols-mainly GSH

Structure-function relationship and physiological role of apelin and its G protein coupled receptor