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doi:10.1016/j.euf.2021.03.024

The Effects of Glucagon-Like Peptide-1 Receptor Agonists on Mitochondrial Function Within Skeletal Muscle: A Systematic Review

Researchers have shown that, by stabilizing blood sugar, improving insulin sensitivity, and reducing glucose spikes, GLP-1s may help lower the metabolic burden placed on tissues over time, which is a key factor in preserving long-term healthspan

Moreover, several PD-associated genes, such as PINK1, Parkin, DJ-1/PARK7, the Leucine-rich repeat kinase2 ( LRRK2 ), the Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 2 ( CHCHD2 ), VPS35 and the tumor necrosis factor receptor associated protein 1 ( TRAP1 ), have been shown to be involved in OXPHOS regulation [88] (Table 2)

10.3390/ijms19061736 55 LiW.KuiL.DemetriosT.GongX.TangM

The Swimming score is related to the left/right position of each fish, where 10 is the leftmost position and 0 is the rightmost position, which corresponds to its physical performance