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Bifidobacterium breve MRx0004 protects against airway inflammation in a severe asthma model by suppressing both neutrophil and eosinophil lung infiltration

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Data availability Data will be made available on reasonable request from the corresponding author (M.H.H.) Abbreviations 5-HT: 5-Hydroxytryptamine AchE: Acetylcholinesterase AST: Astaxanthin BBB: Bloodbrain barrier CAT: Catalase COX2: Cyclooxygenase-2 DAB: 3,3-diaminobenzidine tetrahydrochloride DMSO: Dimethyl sulfoxide DPX: Di-poly cysteine xylene EDTA: Ethylenediamine tetra-acetic acid FPN: Fipronil GABA: Gamma-aminobutyric acid GFAP: Glial fibrillary acidic protein GSH: Reduced glutathione IL-1 : Interleukin-1 IL-6: Interleukin-6 MDA: Malondialdehyde ROS: Reactive oxygen species TNF- : Tumor necrosis factor- T-SOD: Total superoxide dismutase References Richardson, J

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Perhaps most interesting, injectable GHK-Cu administered in one body area (such as thigh muscles) improved healing at distant locations (such as ears), demonstrating true systemic regenerative enhancement