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Integrated preclinical studies combining targeted mouse mutagenesis with pharmacology employing chemically refined agents should accelerate our understanding of biological action

PINK1 and Parkin play important roles in the formation of autophagosome (Forbes and Thorburn, 2018)

Liver Cirrhosis Advanced liver scarring that affects its ability to function properly

Organelles, metabolism, sex differences, and the epigenome are critical gateways to future discoveries in neuroscience, while clinical investigations require a deep understanding of the biology underlying spatial pathology

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95% CI, 5.21 to 1.23